Bimodal regulation of p21(waf1) protein as function of DNA damage levels

Human p21(Waf1) protein is well known for being transcriptionally induced by p53 and activating the cell cycle checkpoint arrest in response to DNA breaks. Here we report that p21(Waf1) protein undergoes a bimodal regulation, being upregulated in response to low doses of DNA damage but rapidly and t...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Buscemi, G, Ricci, C, Zannini, L, Fontanella, E, Plevani, P, Delia, D
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615108/
https://ncbi.nlm.nih.gov/pubmed/25486478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.946852
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