Heterogeneous cell-cycle behavior in response to UVB irradiation by a population of single cancer cells visualized by time-lapse FUCCI imaging

The present study analyzed the heterogeneous cell-cycle dependence and fate of single cancer cells in a population treated with UVB using a fluorescence ubiquitination-based cell-cycle (FUCCI) imaging system. HeLa cells expressing FUCCI were irradiated by 100 or 200 J/m(2) UVB. Modulation of the cel...

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Veröffentlicht in:Cell Cycle
Hauptverfasser: Miwa, Shinji, Yano, Shuya, Kimura, Hiroaki, Yamamoto, Mako, Toneri, Makoto, Murakami, Takashi, Hayashi, Katsuhiro, Yamamoto, Norio, Fujiwara, Toshiyoshi, Tsuchiya, Hiroyuki, Hoffman, Robert M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
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Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615034/
https://ncbi.nlm.nih.gov/pubmed/25946083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1033598
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