Novel Lys63-linked ubiquitination of IKKβ induces STAT3 signaling

NFκB signaling plays a significant role in human disease, including breast and ovarian carcinoma, insulin resistance, embryonic lethality and liver degeneration, rheumatoid arthritis, aging and Multiple Myeloma (MM). Inhibitor of κB (IκB) kinase β (IKKβ) regulates canonical Nuclear Factor κB (NFκB)...

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Publicado en:Cell Cycle
Main Authors: Gallo, Leandro H, Meyer, April N, Motamedchaboki, Khatereh, Nelson, Katelyn N, Haas, Martin, Donoghue, Daniel J
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615003/
https://ncbi.nlm.nih.gov/pubmed/25486864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.988026
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