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RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling

The ATR-Chk1 signaling pathway mediates cellular responses to DNA damage and replication stress and is composed of a number of core factors that are conserved throughout eukaryotic organisms. However, humans and other higher eukaryotic species possess additional factors that are implicated in the re...

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Publicado en:Cell Cycle
Autores principales: Lindsey-Boltz, Laura A, Kemp, Michael G, Capp, Christopher, Sancar, Aziz
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614876/
https://ncbi.nlm.nih.gov/pubmed/25602520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.967076
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