The emerging role of lysine demethylases in DNA damage response: dissecting the recruitment mode of KDM4D/JMJD2D to DNA damage sites

KDM4D is a lysine demethylase that removes tri- and di- methylated residues from H3K9 and is involved in transcriptional regulation and carcinogenesis. We recently showed that KDM4D is recruited to DNA damage sites in a PARP1-dependent manner and facilitates double-strand break repair in human cells...

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Udgivet i:Cell Cycle
Main Authors: Khoury-Haddad, Hanan, Nadar-Ponniah, Prathamesh T, Awwad, Samah, Ayoub, Nabieh
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614868/
https://ncbi.nlm.nih.gov/pubmed/25714495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1014147
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