Caricamento...

Overexpression of KDM4 lysine demethylases disrupts the integrity of the DNA mismatch repair pathway

The KDM4 family of lysine demethylases consists of five members, KDM4A, -B and -C that demethylate H3K9me2/3 and H3K36me2/3 marks, while KDM4D and -E demethylate only H3K9me2/3. Recent studies implicated KDM4 proteins in regulating genomic instability and carcinogenesis. Here, we describe a previous...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Biol Open
Autori principali: Awwad, Samah W., Ayoub, Nabieh
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400592/
https://ncbi.nlm.nih.gov/pubmed/25770186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.201410991
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !