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Overexpression of KDM4 lysine demethylases disrupts the integrity of the DNA mismatch repair pathway
The KDM4 family of lysine demethylases consists of five members, KDM4A, -B and -C that demethylate H3K9me2/3 and H3K36me2/3 marks, while KDM4D and -E demethylate only H3K9me2/3. Recent studies implicated KDM4 proteins in regulating genomic instability and carcinogenesis. Here, we describe a previous...
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| Publicado no: | Biol Open |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4400592/ https://ncbi.nlm.nih.gov/pubmed/25770186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.201410991 |
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