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Fine-tuning the intensity of the PKB/Akt signal enables diverse physiological responses

The PI3K/PDK1/PKB signaling pathway plays essential roles in regulating neuronal survival, differentiation and plasticity in response to neurotrophic factors, neurotransmitters and ion channels. Both PDK1 and PKB can interact at the plasma membrane with a phosphoinositide synthesized by PI3K, the se...

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Detalles Bibliográficos
Publicado en:Cell Cycle
Main Authors: Zhou, Xiangyu, Cordon-Barris, Lluis, Zurashvili, Tinatin, Bayascas, Jose Ramon
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614834/
https://ncbi.nlm.nih.gov/pubmed/25485494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.962954
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