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Fine-tuning the intensity of the PKB/Akt signal enables diverse physiological responses
The PI3K/PDK1/PKB signaling pathway plays essential roles in regulating neuronal survival, differentiation and plasticity in response to neurotrophic factors, neurotransmitters and ion channels. Both PDK1 and PKB can interact at the plasma membrane with a phosphoinositide synthesized by PI3K, the se...
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| Pubblicato in: | Cell Cycle |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4614834/ https://ncbi.nlm.nih.gov/pubmed/25485494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.962954 |
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