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Functional relationship among PLK2, PLK4 and ROCK2 to induce centrosome amplification
The presence of more than 2 centrosomes (centrosome amplification) leads to defective mitosis and chromosome segregation errors, is frequently found in a variety of cancer types, and believed to be the major cause of chromosome instability. One mechanism for generation of amplified centrosomes is ov...
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| Vydáno v: | Cell Cycle |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4614521/ https://ncbi.nlm.nih.gov/pubmed/25590559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.989121 |
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