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Analysis of centrosome localization of BRCA1 and its activity in suppressing centrosomal aster formation
BRCA1, a product of a familial breast and ovarian cancer susceptibility gene, localizes to centrosomes and physically interacts with γ-tubulin, a key centrosomal protein for microtubule nucleation and anchoring at centrosomes. Here, we performed a rigorous analysis of centrosome localization of BRCA...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3419063/ https://ncbi.nlm.nih.gov/pubmed/22833046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21396 |
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