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IDH mutations in liver cell plasticity and biliary cancer

Intrahepatic cholangiocarcinoma (ICC) is an aggressive cancer associated with the bile ducts within the liver. These tumors are characterized by frequent gain-of-function mutations in the isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) genes—that are also common in subsets of neural, haematopoietic...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Saha, Supriya K, Parachoniak, Christine A, Bardeesy, Nabeel
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614372/
https://ncbi.nlm.nih.gov/pubmed/25485496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.965054
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