Epithelial cell-derived periostin functions as a tumor suppressor in gastric cancer through stabilizing p53 and E-cadherin proteins via the Rb/E2F1/p14ARF/Mdm2 signaling pathway

Periostin is usually considered as an oncogene in diverse human cancers, including breast, prostate, colon, esophagus, and pancreas cancers, whereas it acts as a tumor suppressor in bladder cancer. In gastric cancer, it has been demonstrated that periglandular periostin expression is decreased where...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Lv, Hongjun, Liu, Rui, Fu, Jiao, Yang, Qi, Shi, Jing, Chen, Pu, Ji, Meiju, Shi, Bingyin, Hou, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614259/
https://ncbi.nlm.nih.gov/pubmed/25486483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.947203
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