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High-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical Interactions

Detection of drug-drug interactions is essential during the early stages of drug discovery and development, and the understanding of drug-botanical interactions is important for the safe use of botanical dietary supplements. Among the different forms of drug interactions that are known, inhibition o...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Li, Guannan, Huang, Ke, Nikolic, Dejan, van Breemen, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613945/
https://ncbi.nlm.nih.gov/pubmed/26285764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.065987
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