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Safeguarding genome stability: RASSF1A tumor suppressor regulates BRCA2 at stalled forks

While it has been widely established that defective fork restart after exposure to stress results in increased genomic instability, the importance of fork protection during stalling for safeguarding genomic integrity has recently been fully appreciated. BRCA2, Breast tumor suppressor, has dual funct...

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Publicat a:Cell Cycle
Autors principals: Pefani, Dafni Eleftheria, O'Neill, Eric
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613848/
https://ncbi.nlm.nih.gov/pubmed/25927241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1035845
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