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Safeguarding genome stability: RASSF1A tumor suppressor regulates BRCA2 at stalled forks

While it has been widely established that defective fork restart after exposure to stress results in increased genomic instability, the importance of fork protection during stalling for safeguarding genomic integrity has recently been fully appreciated. BRCA2, Breast tumor suppressor, has dual funct...

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Pefani, Dafni Eleftheria, O'Neill, Eric
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613848/
https://ncbi.nlm.nih.gov/pubmed/25927241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1035845
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