Discrete Functions of Nuclear Receptor Rev-erbα Couple Metabolism to the Clock

Circadian and metabolic physiology are intricately intertwined, as illustrated by Rev-erbα, a transcription factor (TF) that functions both as a core repressive component of the cell autonomous clock and as a regulator of metabolic genes. Here we show that Rev-erbα modulates the clock and metabolism...

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Bibliographic Details
Published in:Science
Main Authors: Zhang, Yuxiang, Fang, Bin, Emmett, Matthew J., Damle, Manashree, Sun, Zheng, Feng, Dan, Armour, Sean M., Remsberg, Jarrett R., Jager, Jennifer, Soccio, Raymond E., Steger, David J., Lazar, Mitchell A.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613749/
https://ncbi.nlm.nih.gov/pubmed/26044300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab3021
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