Lineage-Specific Viral Hijacking of Non-Canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity

HIV-1 encodes the accessory protein Vif, which hijacks a host Cullin-RING ubiquitin ligase (CRL) complex as well as the non-canonical cofactor CBFβ, to antagonize APOBEC3 antiviral proteins. Non-canonical cofactor recruitment to CRL complexes by viral factors, to date, has only been attributed to HI...

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Publicado en:Cell Rep
Autores principales: Kane, Joshua R., Stanley, David J., Hultquist, Judd F., Johnson, Jeffrey R., Mietrach, Nicole, Binning, Jennifer M., Jónsson, Stefán R., Barelier, Sarah, Newton, Billy W., Johnson, Tasha L., Franks-Skiba, Kathleen E., Li, Ming, Brown, William L., Fraser, James S., Harris, Reuben S., Andrésdóttir, Valgerđur, Gross, John D., Krogan, Nevan J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613747/
https://ncbi.nlm.nih.gov/pubmed/25981045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.04.038
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