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Expanding the Catalytic Triad in Epoxide Hydrolases and Related Enzymes

[Image: see text] Potato epoxide hydrolase 1 exhibits rich enantio- and regioselectivity in the hydrolysis of a broad range of substrates. The enzyme can be engineered to increase the yield of optically pure products as a result of changes in both enantio- and regioselectivity. It is thus highly att...

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發表在:ACS Catal
Main Authors: Amrein, Beat A., Bauer, Paul, Duarte, Fernanda, Janfalk Carlsson, Åsa, Naworyta, Agata, Mowbray, Sherry L., Widersten, Mikael, Kamerlin, Shina C. L.
格式: Artigo
語言:Inglês
出版: American Chemical Society 2015
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613740/
https://ncbi.nlm.nih.gov/pubmed/26527505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.5b01639
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