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Identification of a mitochondrial-binding site on the N-terminal end of hexokinase II

Hexokinase II (HKII) is responsible for the first step in the glycolysis pathway by adding a phosphate on to the glucose molecule so it can proceed down the pathway to produce the energy for continuous cancer cell growth. Tumour cells overexpress the HKII enzyme. In fact, it is the overexpression of...

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Bibliografiske detaljer
Udgivet i:Biosci Rep
Main Authors: Bryan, Nadezda, Raisch, Kevin P.
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613670/
https://ncbi.nlm.nih.gov/pubmed/26182367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20150047
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