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Identification of a mitochondrial-binding site on the N-terminal end of hexokinase II

Hexokinase II (HKII) is responsible for the first step in the glycolysis pathway by adding a phosphate on to the glucose molecule so it can proceed down the pathway to produce the energy for continuous cancer cell growth. Tumour cells overexpress the HKII enzyme. In fact, it is the overexpression of...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biosci Rep
Main Authors: Bryan, Nadezda, Raisch, Kevin P.
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613670/
https://ncbi.nlm.nih.gov/pubmed/26182367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20150047
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