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Glucose Phosphorylation and Mitochondrial Binding Are Required for the Protective Effects of Hexokinases I and II

Alterations in glucose metabolism have been demonstrated for diverse disorders ranging from heart disease to cancer. The first step in glucose metabolism is carried out by the hexokinase (HK) family of enzymes. HKI and II can bind to mitochondria through their N-terminal hydrophobic regions, and the...

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Detalhes bibliográficos
Main Authors: Sun, Lin, Shukair, Shetha, Naik, Tejaswitha Jairaj, Moazed, Farzad, Ardehali, Hossein
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223386/
https://ncbi.nlm.nih.gov/pubmed/18039843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00224-07
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