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Glucose Phosphorylation and Mitochondrial Binding Are Required for the Protective Effects of Hexokinases I and II
Alterations in glucose metabolism have been demonstrated for diverse disorders ranging from heart disease to cancer. The first step in glucose metabolism is carried out by the hexokinase (HK) family of enzymes. HKI and II can bind to mitochondria through their N-terminal hydrophobic regions, and the...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2223386/ https://ncbi.nlm.nih.gov/pubmed/18039843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00224-07 |
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