FANCD2 influences replication fork processes and genome stability in response to clustered DSBs

Fanconi Anemia (FA) is a cancer predisposition syndrome and the factors defective in FA are involved in DNA replication, DNA damage repair and tumor suppression. Here, we show that FANCD2 is critical for genome stability maintenance in response to high-linear energy transfer (LET) radiation. We foun...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Zhu, Jiayun, Su, Fengtao, Mukherjee, Shibani, Mori, Eiichiro, Hu, Burong, Asaithamby, Aroumougame
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613663/
https://ncbi.nlm.nih.gov/pubmed/26083937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1036210
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