FANCD2 influences replication fork processes and genome stability in response to clustered DSBs

Fanconi Anemia (FA) is a cancer predisposition syndrome and the factors defective in FA are involved in DNA replication, DNA damage repair and tumor suppression. Here, we show that FANCD2 is critical for genome stability maintenance in response to high-linear energy transfer (LET) radiation. We foun...

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Publicat a:Cell Cycle
Autors principals: Zhu, Jiayun, Su, Fengtao, Mukherjee, Shibani, Mori, Eiichiro, Hu, Burong, Asaithamby, Aroumougame
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613663/
https://ncbi.nlm.nih.gov/pubmed/26083937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1036210
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