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Cell-cycle fate-monitoring distinguishes individual chemosensitive and chemoresistant cancer cells in drug-treated heterogeneous populations demonstrated by real-time FUCCI imaging

Essentially every population of cancer cells within a tumor is heterogeneous, especially with regard to chemosensitivity and resistance. In the present study, we utilized the fluorescence ubiquitination-based cell cycle indicator (FUCCI) imaging system to investigate the correlation between cell-cyc...

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發表在:Cell Cycle
Main Authors: Miwa, Shinji, Yano, Shuya, Kimura, Hiroaki, Yamamoto, Mako, Toneri, Makoto, Matsumoto, Yasunori, Uehara, Fuminari, Hiroshima, Yukihiko, Murakami, Takashi, Hayashi, Katsuhiro, Yamamoto, Norio, Bouvet, Michael, Fujiwara, Toshiyoshi, Tsuchiya, Hiroyuki, Hoffman, Robert M
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613186/
https://ncbi.nlm.nih.gov/pubmed/25551170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.991604
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