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RhoA activity increased in myocardium of arrhythmogenic cardiomyopathy patients and affected connexin 43 protein expression in HL-1 cells

Arrhythmogenic cardiomyopathy (AC) is a familial heart muscle disease with mutations of desmosomal gene and its pathogenesis is related with mutations of desmosomal gene and abnormality of connexin43 (Cx43). One of Rho GTPase, RhoA involves in many pathological processes and is regulated by desmosom...

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Foilsithe in:Int J Clin Exp Med
Main Authors: Wang, Li, Liu, Shenghua, Zhang, Hongliang, Hu, Shengshou, Wei, Yingjie
Formáid: Artigo
Teanga:Inglês
Foilsithe: e-Century Publishing Corporation 2015
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612892/
https://ncbi.nlm.nih.gov/pubmed/26550207
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