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RhoA activity increased in myocardium of arrhythmogenic cardiomyopathy patients and affected connexin 43 protein expression in HL-1 cells

Arrhythmogenic cardiomyopathy (AC) is a familial heart muscle disease with mutations of desmosomal gene and its pathogenesis is related with mutations of desmosomal gene and abnormality of connexin43 (Cx43). One of Rho GTPase, RhoA involves in many pathological processes and is regulated by desmosom...

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Bibliographic Details
Published in:Int J Clin Exp Med
Main Authors: Wang, Li, Liu, Shenghua, Zhang, Hongliang, Hu, Shengshou, Wei, Yingjie
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612892/
https://ncbi.nlm.nih.gov/pubmed/26550207
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