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Abnormal connexin43 in arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 mutations

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a disorder of cardiomyocyte intercalated disk proteins causing sudden death. Heterozygous mutations of the desmosomal protein plakophilin-2 (PKP-2) are the commonest genetic cause of ARVC. Abnormal gap junction connexin43 expression has been...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Fidler, Lee M, Wilson, Gregory J, Liu, Fanfan, Cui, Xuezhi, Scherer, Stephen W, Taylor, Glenn P, Hamilton, Robert M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496128/
https://ncbi.nlm.nih.gov/pubmed/18662195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00438.x
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