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VEGF silencing inhibits human osteosarcoma angiogenesis and promotes cell apoptosis via PI3K/AKT signaling pathway

Vascular endothelial growth factor (VEGF) is one of the most potently angiogenic factors which promotes generation of tumor vasculature. VEGF is usually up-regulated in multiple cancers include osteosarcoma and gliomas. To further explore the potential molecular mechanism that inhibits tumor growth...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Zhao, Jian, Zhang, Zi-Ru, Zhao, Na, Ma, Bao-An, Fan, Qing-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612837/
https://ncbi.nlm.nih.gov/pubmed/26550152
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