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Apiosporamide, A 4-hydroxy-2-pyridone Alkaloid, Induces Apoptosis Via PI3K/Akt Signaling Pathway In Osteosarcoma Cells

BACKGROUND: Osteosarcoma (OS) is a common primary malignant bone tumour in children and young adults. Apiosporamide, a 4-hydroxy-2-pyridone alkaloid from a deep-sea-derived fungus, Arthrinium sp. UJNMF0008, showed anti-proliferative effects toward a panel of human cancer cell lines, and the molecula...

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Bibliografiska uppgifter
I publikationen:Onco Targets Ther
Huvudupphovsmän: Zhang, Yuying, Zhang, Qianqian, Bao, Jie, Huang, Jintian, Zhang, Hua
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814361/
https://ncbi.nlm.nih.gov/pubmed/31695421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S218692
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