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Silencing of VEGF inhibits human osteosarcoma angiogenesis and promotes cell apoptosis via VEGF/PI3K/AKT signaling pathway

Background: Osteosarcoma is a kind of highly malignant tumor and the growth and metastasis is closely related to angiogenesis. Vascular endothelial growth factor (VEGF) is an important angiogenesis-promoting factor. In the current study, we investigated the effects of suppressed VEGF on osteosarcoma...

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Publicat a:Am J Transl Res
Autors principals: Peng, Ningning, Gao, Shuming, Guo, Xu, Wang, Guangya, Cheng, Cai, Li, Min, Liu, Kehun
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846943/
https://ncbi.nlm.nih.gov/pubmed/27158386
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