The metabolically-modulated stem cell niche: a dynamic scenario regulating cancer cell phenotype and resistance to therapy

This Perspective addresses the interactions of cancer stem cells (CSC) with environment which result in the modulation of CSC metabolism, and thereby of CSC phenotype and resistance to therapy. We considered first as a model disease chronic myeloid leukemia (CML), which is triggered by a well-identi...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Rovida, Elisabetta, Peppicelli, Silvia, Bono, Silvia, Bianchini, Francesca, Tusa, Ignazia, Cheloni, Giulia, Marzi, Ilaria, Cipolleschi, Maria Grazia, Calorini, Lido, Sbarba, Persio Dello
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Perspectives
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612663/
https://ncbi.nlm.nih.gov/pubmed/25485495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.964107
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