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Organocatalytic one-pot 1,4-/1,6-/1,2-addition sequence for the stereocontrolled formation of six consecutive stereocenters

An unprecedented stereoselective organocatalytic one-pot 1,4-/1,6-/1,2-addition sequence between β-dicarbonyl compounds, β-nitroalkenes and 4-nitro-5-styrylisoxazoles sequentially catalyzed by low loading of a squaramide catalyst and an achiral base has been developed. The protocol opens an efficien...

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Publicat a:Chem Commun (Camb)
Autors principals: Chauhan, Pankaj, Mahajan, Suruchi, Raabe, Gerhard, Enders, Dieter
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612129/
https://ncbi.nlm.nih.gov/pubmed/25563802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc09730k
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