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Asymmetric synthesis of functionalized cyclohexanes bearing five stereocenters via a one-pot organocatalytic Michael–Michael–1,2-addition sequence
A highly stereoselective one-pot procedure involving an enantioselective Michael addition promoted by low loading of an amino-squaramide catalyst followed by an achiral base catalyzed domino Michael–Knoevenagel-type 1,2-addition sequence provides efficient access to fully substituted cyclohexanes be...
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| 發表在: | Chem Commun (Camb) |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Royal Society of Chemistry
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4268544/ https://ncbi.nlm.nih.gov/pubmed/24842728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc01885k |
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