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Asymmetric synthesis of functionalized cyclohexanes bearing five stereocenters via a one-pot organocatalytic Michael–Michael–1,2-addition sequence

A highly stereoselective one-pot procedure involving an enantioselective Michael addition promoted by low loading of an amino-squaramide catalyst followed by an achiral base catalyzed domino Michael–Knoevenagel-type 1,2-addition sequence provides efficient access to fully substituted cyclohexanes be...

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書目詳細資料
發表在:Chem Commun (Camb)
Main Authors: Chauhan, Pankaj, Urbanietz, Gregor, Raabe, Gerhard, Enders, Dieter
格式: Artigo
語言:Inglês
出版: Royal Society of Chemistry 2014
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268544/
https://ncbi.nlm.nih.gov/pubmed/24842728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc01885k
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