Autism-like syndrome is induced by pharmacological suppression of BET proteins in young mice

Studies investigating the causes of autism spectrum disorder (ASD) point to genetic, as well as epigenetic, mechanisms of the disease. Identification of epigenetic processes that contribute to ASD development and progression is of major importance and may lead to the development of novel therapeutic...

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Vydáno v:J Exp Med
Hlavní autoři: Sullivan, Josefa M., Badimon, Ana, Schaefer, Uwe, Ayata, Pinar, Gray, James, Chung, Chun-wa, von Schimmelmann, Melanie, Zhang, Fan, Garton, Neil, Smithers, Nicholas, Lewis, Huw, Tarakhovsky, Alexander, Prinjha, Rab K., Schaefer, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2015
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612093/
https://ncbi.nlm.nih.gov/pubmed/26392221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151271
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