Inhibition of BET Proteins Reduces Right Ventricle Hypertrophy and Pulmonary Hypertension Resulting from Combined Hypoxia and Pulmonary Inflammation

Pulmonary hypertension is a co-morbidity, which strongly participates in morbi-mortality in patients with chronic obstructive pulmonary disease (COPD). Recent findings showed that bromodomain-containing proteins, in charge of reading histone acetylation, could be involved in pulmonary arterial hyper...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chabert, Clovis, Khochbin, Saadi, Rousseaux, Sophie, Veyrenc, Sylvie, Furze, Rebecca, Smithers, Nicholas, Prinjha, Rab K, Schlattner, Uwe, Pison, Christophe, Dubouchaud, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121304/
https://ncbi.nlm.nih.gov/pubmed/30061518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082224
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