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Structural and evolutionary relationships of “AT-less” type I polyketide synthase ketosynthases

Acyltransferase (AT)-less type I polyketide synthases (PKSs) break the type I PKS paradigm. They lack the integrated AT domains within their modules and instead use a discrete AT that acts in trans, whereas a type I PKS module minimally contains AT, acyl carrier protein (ACP), and ketosynthase (KS)...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Lohman, Jeremy R., Ma, Ming, Osipiuk, Jerzy, Nocek, Boguslaw, Kim, Youngchang, Chang, Changsoo, Cuff, Marianne, Mack, Jamey, Bigelow, Lance, Li, Hui, Endres, Michael, Babnigg, Gyorgy, Joachimiak, Andrzej, Phillips, George N., Shen, Ben
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611616/
https://ncbi.nlm.nih.gov/pubmed/26420866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515460112
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