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ShRNA-mediated gene silencing of β-catenin inhibits growth of human colon cancer cells

AIM: To observe the gene silencing mediated by the specific shRNA targeted against β-catenin and its effect on cell proliferation and cycle distribution in the human colon cancer cell line Colo205. METHODS: Two shRNA plasmid vectors against β-catenin were constructed and transfected into Colo205 cel...

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Bibliografske podrobnosti
izdano v:World J Gastroenterol
Main Authors: Huang, Wen-Sheng, Wang, Jian-Ping, Wang, Ting, Fang, Jie-Yu, Lan, Ping, Ma, Jin-Ping
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Co., Limited 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611300/
https://ncbi.nlm.nih.gov/pubmed/18161931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i48.6581
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