Silencing of the hTERT Gene by shRNA Inhibits Colon Cancer SW480 Cell Growth In Vitro and In Vivo

Human telomerase reverse transcriptase (hTERT) is the key enzyme responsible for synthesizing and maintaining the telomeres on the ends of chromosomes, and it is essential for cell proliferation. This has made hTERT a focus of oncology research and an attractive target for anticancer drug developmen...

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Detalhes bibliográficos
Main Authors: Liu, Ai-Qun, Ge, Lian-Ying, Lu, Xiao-Ling, Luo, Xiao-Ling, Cai, Yan-Ling, Ye, Xing-Qing, Geng, Fang-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160217/
https://ncbi.nlm.nih.gov/pubmed/25207650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107019
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