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CCR5-dependent activation of mTORC1 regulates translation of iNOS and COX-2 during EMCV infection

Encephalomyocarditis virus (EMCV) infection of macrophages results in the expression of a number of inflammatory and anti-viral genes including inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2. EMCV-induced macrophage activation has been shown to require the presence of CCR5 and the...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Shaheen, Zachary R., Naatz’, Aaron, Corbett, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610876/
https://ncbi.nlm.nih.gov/pubmed/26408666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500704
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