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Tandem Prenyltransferases Catalyze Isoprenoid Elongation and Complexity Generation in Biosynthesis of Quinolone Alkaloids

Modification of natural products with prenyl groups and the ensuing oxidative transformations are important for introducing structural complexity and biological activities. Understanding the different mechanisms Nature performs prenylation can lead to new enzymatic tools. Penigequinolones (1) are po...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Zou, Yi, Zhan, Zhajun, Li, Dehai, Tang, Mancheng, Watanabe, Kenji, Tang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610815/
https://ncbi.nlm.nih.gov/pubmed/25859931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b03022
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