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Enzyme-Catalyzed Azepinoindole Formation in Clavine Alkaloid Biosynthesis

(−)-Aurantioclavine (1), which contains a characteristic seven-membered ring fused to an indole ring, belongs to the azepinoindole class of fungal clavine alkaloids. Here we show that, starting from a 4-dimethylallyl-l-tryptophan precursor, a flavin adenine dinucleotide (FAD)-binding oxidase and a c...

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Dades bibliogràfiques
Publicat a:Org Lett
Autors principals: Chen, Kuan-Lin, Lai, Chen-Yu, Pham, Mai-Truc, Chein, Rong-Jie, Tang, Yi, Lin, Hsiao-Ching
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092377/
https://ncbi.nlm.nih.gov/pubmed/32243182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c01132
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