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Palladium-Catalyzed α-Arylation of Aryl Acetic Acid Derivatives via Dienolate Intermediates with Aryl Chlorides and Bromides

[Image: see text] To date, examples of α-arylation of carboxylic acids remain scarce. Using a deprotonative cross-coupling process (DCCP), a method for palladium-catalyzed γ-arylation of aryl acetic acids with aryl halides has been developed. This protocol is applicable to a wide range of aryl bromi...

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Publicat a:Org Lett
Autors principals: Sha, Sheng-Chun, Zhang, Jiadi, Walsh, Patrick J.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2015
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610326/
https://ncbi.nlm.nih.gov/pubmed/25582024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol503545j
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