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Palladium-Catalyzed α-Arylation of Aryl Acetic Acid Derivatives via Dienolate Intermediates with Aryl Chlorides and Bromides
[Image: see text] To date, examples of α-arylation of carboxylic acids remain scarce. Using a deprotonative cross-coupling process (DCCP), a method for palladium-catalyzed γ-arylation of aryl acetic acids with aryl halides has been developed. This protocol is applicable to a wide range of aryl bromi...
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| Veröffentlicht in: | Org Lett |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American
Chemical Society
2015
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4610326/ https://ncbi.nlm.nih.gov/pubmed/25582024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol503545j |
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