OTX2 exhibits cell-context-dependent effects on cellular and molecular properties of human embryonic neural precursors and medulloblastoma cells

Medulloblastoma (MB) is the most common malignant primary pediatric brain tumor and is currently divided into four subtypes based on different genomic alterations, gene expression profiles and response to treatment: WNT, Sonic Hedgehog (SHH), Group 3 and Group 4. This extensive heterogeneity has mad...

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Библиографические подробности
Опубликовано в: :Dis Model Mech
Главные авторы: Kaur, Ravinder, Aiken, Christopher, Morrison, Ludivine Coudière, Rao, Radhika, Del Bigio, Marc R., Rampalli, Shravanti, Werbowetski-Ogilvie, Tamra
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610233/
https://ncbi.nlm.nih.gov/pubmed/26398939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020594
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