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OTX2 exhibits cell-context-dependent effects on cellular and molecular properties of human embryonic neural precursors and medulloblastoma cells

Medulloblastoma (MB) is the most common malignant primary pediatric brain tumor and is currently divided into four subtypes based on different genomic alterations, gene expression profiles and response to treatment: WNT, Sonic Hedgehog (SHH), Group 3 and Group 4. This extensive heterogeneity has mad...

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Bibliografski detalji
Izdano u:Dis Model Mech
Glavni autori: Kaur, Ravinder, Aiken, Christopher, Morrison, Ludivine Coudière, Rao, Radhika, Del Bigio, Marc R., Rampalli, Shravanti, Werbowetski-Ogilvie, Tamra
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610233/
https://ncbi.nlm.nih.gov/pubmed/26398939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020594
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