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OTX2 exhibits cell-context-dependent effects on cellular and molecular properties of human embryonic neural precursors and medulloblastoma cells

Medulloblastoma (MB) is the most common malignant primary pediatric brain tumor and is currently divided into four subtypes based on different genomic alterations, gene expression profiles and response to treatment: WNT, Sonic Hedgehog (SHH), Group 3 and Group 4. This extensive heterogeneity has mad...

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Detalles Bibliográficos
Publicado en:Dis Model Mech
Main Authors: Kaur, Ravinder, Aiken, Christopher, Morrison, Ludivine Coudière, Rao, Radhika, Del Bigio, Marc R., Rampalli, Shravanti, Werbowetski-Ogilvie, Tamra
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610233/
https://ncbi.nlm.nih.gov/pubmed/26398939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020594
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