OTX2 exhibits cell-context-dependent effects on cellular and molecular properties of human embryonic neural precursors and medulloblastoma cells

Medulloblastoma (MB) is the most common malignant primary pediatric brain tumor and is currently divided into four subtypes based on different genomic alterations, gene expression profiles and response to treatment: WNT, Sonic Hedgehog (SHH), Group 3 and Group 4. This extensive heterogeneity has mad...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Dis Model Mech
Prif Awduron: Kaur, Ravinder, Aiken, Christopher, Morrison, Ludivine Coudière, Rao, Radhika, Del Bigio, Marc R., Rampalli, Shravanti, Werbowetski-Ogilvie, Tamra
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610233/
https://ncbi.nlm.nih.gov/pubmed/26398939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.020594
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