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“Store-operated” cAMP signaling contributes to Ca(2+)-activated Cl(−) secretion in T84 colonic cells
Apical cAMP-dependent CFTR Cl(−) channels are essential for efficient vectorial movement of ions and fluid into the lumen of the colon. It is well known that Ca(2+)-mobilizing agonists also stimulate colonic anion secretion. However, CFTR is apparently not activated directly by Ca(2+), and the exist...
Zapisane w:
| Wydane w: | Am J Physiol Gastrointest Liver Physiol |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Physiological Society
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4609931/ https://ncbi.nlm.nih.gov/pubmed/26316590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00214.2015 |
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