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Epigenetic Regulation of Werner Syndrome Gene in Age-Related Cataract

Purpose. To examine the promoter methylation and histone modification of WRN (Werner syndrome gene), a DNA repair gene, and their relationship with the gene expression in age-related cataract (ARC) lens. Methods. We collected the lenses after cataract surgery from 117ARC patients and 39 age-matched...

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Dades bibliogràfiques
Publicat a:J Ophthalmol
Autors principals: Zhu, Xi, Zhang, Guowei, Kang, Lihua, Guan, Huaijin
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609838/
https://ncbi.nlm.nih.gov/pubmed/26509079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/579695
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