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Tristetraprolin Recruits Eukaryotic Initiation Factor 4E2 To Repress Translation of AU-Rich Element-Containing mRNAs

Tristetraprolin (TTP) regulates the expression of AU-rich element-containing mRNAs through promoting the degradation and repressing the translation of target mRNA. While the mechanism for promoting target mRNA degradation has been extensively studied, the mechanism underlying translational repressio...

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Publicat a:Mol Cell Biol
Autors principals: Tao, Xianzun, Gao, Guangxia
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609744/
https://ncbi.nlm.nih.gov/pubmed/26370510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00845-15
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