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Spatial Interplay between Polycomb and Trithorax Complexes Controls Transcriptional Activity in T Lymphocytes

Trithorax group (TrxG) and Polycomb group (PcG) proteins are two mutually antagonistic chromatin modifying complexes, however, how they together mediate transcriptional counter-regulation remains unknown. Genome-wide analysis revealed that binding of Ezh2 and menin, central members of the PcG and Tr...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Onodera, Atsushi, Tumes, Damon J., Watanabe, Yukiko, Hirahara, Kiyoshi, Kaneda, Atsushi, Sugiyama, Fumihiro, Suzuki, Yutaka, Nakayama, Toshinori
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609743/
https://ncbi.nlm.nih.gov/pubmed/26324324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00677-15
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