STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells

Polycomb group (PcG) and trithorax group (TrxG) complexes exert opposing effects on the maintenance of the transcriptional status of the developmentally regulated Hox genes. In this study, we show that activation of STAT6 induces displacement of the PcG complex by the TrxG complex at the upstream re...

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Detalhes bibliográficos
Main Authors: Onodera, Atsushi, Yamashita, Masakatsu, Endo, Yusuke, Kuwahara, Makoto, Tofukuji, Soichi, Hosokawa, Hiroyuki, Kanai, Akinori, Suzuki, Yutaka, Nakayama, Toshinori
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964576/
https://ncbi.nlm.nih.gov/pubmed/20956546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100760
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