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Site-selective Characterization of Src Homology 3 Domain Molecular Recognition with Cyanophenylalanine Infrared Probes

Local heterogeneity of microenvironments in proteins is important in biological function, but difficult to characterize experimentally. One approach is the combination of infrared (IR) spectroscopy and site-selective incorporation of probe moieties with spectrally resolved IR absorptions that enable...

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Détails bibliographiques
Publié dans:Anal Methods
Auteurs principaux: Horness, Rachel E., Basom, Edward J., Thielges, Megan C.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609639/
https://ncbi.nlm.nih.gov/pubmed/26491469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C5AY00523J
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